Podcasts > The School of Greatness > No. 1 RISK FACTOR to Your Health: INFLAMMATION (What it is, & How to Reduce it)

No. 1 RISK FACTOR to Your Health: INFLAMMATION (What it is, & How to Reduce it)

By Lewis Howes

On this episode of The School of Greatness, the discussion focuses on the importance of managing inflammation, a natural immune response that can become chronic and lead to various health issues. Guests offer practical lifestyle changes, like adopting an anti-inflammatory diet rich in plant-based foods and spices, adequate sleep, and stress reduction techniques to control inflammation.

The conversation delves into the crucial role of quality sleep in brain function, immune regulation, and overall well-being. Listeners gain insight into developing healthy sleep habits and the impact of sleep deprivation. Additionally, the guests share guidance on making better food and beverage choices, highlighting the inflammatory effects of processed and sugary items versus the benefits of whole, nutrient-dense options.

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No. 1 RISK FACTOR to Your Health: INFLAMMATION (What it is, & How to Reduce it)

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No. 1 RISK FACTOR to Your Health: INFLAMMATION (What it is, & How to Reduce it)

1-Page Summary

Inflammation and its Management

Importance of Inflammation

Per William Li, inflammation is a normal immune response that helps the body defend against infections and heal injuries. However, chronic inflammation can lead to various health issues.

Managing Inflammation Through Lifestyle

Li and Weil recommend lifestyle changes like a healthy diet, adequate sleep, and stress reduction to control inflammation.

Inflammatory Foods

Li warns that processed meats, sugary beverages like soda, and ultra-processed foods can increase inflammation due to high sugar content overloading the body.

Anti-Inflammatory Foods

Li mentions anti-inflammatory foods like cranberries, chocolate, vitamin C-rich fruits, and spices. A plant-based diet rich in omega-3s may also help reduce inflammation.

Supplements for Inflammation

Li and Weil suggest anti-inflammatory supplements such as mushroom extracts, antioxidants like turmeric and ginger, omega-3s from fish oil, and CoQ10.

The Importance of Sleep and its Effects

Sleep Impacts Health

Per Li, adequate, high-quality sleep is crucial for cognitive performance, immune function, metabolic regulation, and anti-aging processes. Sleep deprivation can impair these functions.

Developing Good Sleep Habits

Stevenson emphasizes developing consistent sleep habits like sticking to a schedule and minimizing light exposure to improve sleep quality and health outcomes.

Sleep and Brain Function

Li notes the brain's waste removal system is most active during sleep, crucial for preventing buildup linked to neurological disorders. Sleep allows brain repair processes.

Healthy and Unhealthy Foods and Beverages

Sugary Beverages

Weil and Li advise avoiding sugary beverages like soda and juice due to high sugar content contributing to inflammation and gut issues. Artificial sweeteners may be worse.

Whole Foods

Li advocates for fruits, vegetables, nuts, and whole grains which provide anti-inflammatory antioxidants, fiber, and beneficial compounds lacking in processed foods.

Beneficial Teas

Weil praises matcha green tea for its anti-inflammatory, antioxidant properties from its whole leaf consumption and processing methods concentrating beneficial compounds.

1-Page Summary

Additional Materials

Counterarguments

  • While inflammation is a normal immune response, not all forms of inflammation are beneficial; some can be a sign of an underlying problem that doesn't involve healing or defense against infections.
  • The link between chronic inflammation and various health issues is complex, and while lifestyle changes can have a positive impact, they are not a cure-all and may not address the root causes of inflammation in all individuals.
  • Some processed meats and ultra-processed foods can be part of a balanced diet when consumed in moderation, and not all are equally inflammatory.
  • The recommendation to avoid sugary beverages is generally sound, but in moderation, these drinks can be part of an overall balanced diet without necessarily leading to inflammation or gut issues for everyone.
  • The role of artificial sweeteners in health is debated, and some research suggests they may be a safe alternative to sugar for some people, especially those managing diabetes or obesity.
  • While a plant-based diet rich in omega-3s can be anti-inflammatory, it's important to note that not all plant-based diets are created equal, and some may lack essential nutrients if not carefully planned.
  • The efficacy of supplements in managing inflammation is subject to individual variation, and some may interact with medications or may not be necessary if a person's diet is already well-balanced.
  • The importance of sleep is well-documented, but the relationship between sleep and health can be bidirectional, with poor health also leading to sleep disturbances.
  • The idea that consistent sleep habits will improve sleep quality and health outcomes may not account for individual variations in sleep needs and patterns.
  • While matcha green tea is praised for its properties, it's important to recognize that not everyone may experience the same benefits, and in some cases, high consumption could lead to excessive caffeine intake.
  • Emphasizing whole foods is beneficial, but it's also important to recognize that not all processed foods are unhealthy and that they can be part of a convenient and balanced diet.

Actionables

  • You can create a personalized anti-inflammatory spice blend by mixing turmeric, ginger, and other spices you enjoy, and incorporate it into your daily meals for added flavor and health benefits. Start by experimenting with different ratios in a small batch, then use your custom blend to season vegetables, rice, or protein sources. This not only makes your meals more interesting but also ensures you're consistently consuming anti-inflammatory spices.
  • Develop a bedtime ritual that includes activities promoting relaxation and sleep, such as reading a physical book under warm, low lighting, or practicing a short series of yoga stretches designed to prepare your body for rest. By doing this consistently, you signal to your body that it's time to wind down, which can improve your sleep quality and contribute to the brain's waste removal process mentioned as being most active during sleep.
  • Swap out your afternoon soda or sugary beverage for a homemade iced matcha green tea, using whole matcha powder and a touch of honey if needed. This not only reduces your sugar intake but also provides you with the anti-inflammatory and antioxidant benefits of matcha. To make it more enjoyable, you can add fresh mint or lemon for flavor variety.

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No. 1 RISK FACTOR to Your Health: INFLAMMATION (What it is, & How to Reduce it)

Inflammation and its Management

Inflammation, a fundamental immune response, helps the body defend against infections and is critical for healing. William Li and Shawn Stevenson explain how inflammation functions and why managing it is pivotal, including through diet, sleep, and other lifestyle factors.

Inflammation is a normal immune response that helps the body defend against infections and promote healing

Inflammation is an essential part of the body's immune system. William Li states that it occurs when the body is fighting off invasions such as bacteria or viruses, and it's designed to bring nourishment and immune activity to areas that are injured or under attack. However, it's essential that inflammation remains controlled and localized to prevent potential destruction.

Acute inflammation is a short-term response to an injury or infection, but chronic inflammation can lead to various health issues

While acute inflammation is a normal response to things like cuts or infections, chronic inflammation is prolonged and can contribute to diseases such as cardiovascular, neurodegenerative diseases, and cancer. Li likens chronic inflammation to a car radio's volume which won't turn down, escalating continuously instead of subsiding.

Managing inflammation through lifestyle factors like diet, sleep, and stress reduction is important

Experts suggest lifestyle changes are critical in managing inflammation. Li recommends methods such as calming oneself, meditation, and ensuring adequate sleep, while Weil also emphasizes the management of chronic inflammation for better health.

Certain foods like processed meats, sugary beverages, and ultra-processed foods can increase inflammation

William Li warns that foods and beverages such as sodas can cause inflammation due to the overload of sugar on the body's capacity, and he advises cutting down the intake by at least one can a day to manage inflammation. Additionally, artificial sweeteners may be even more damaging to the gut microbiome than regular sugars.

The mainstream North American diet is known to be pro-inflammatory due to the types of fats and carbs consumed, and the lack of protective elements found in fruits, vegetables, herbs, spices, and tea.

Omega-3 rich foods, anti-inflammatory spices, and a plant-based diet can help reduce inflammation

Li talks about foods with anti-inflammatory properties, specifically naming items like cranberries, chocolate, vitamin C, strawberries, guava, and red bell peppers. While it is not specifically mentioned by Li, a discussion on an anti-inflammatory diet might suggest incorporat ...

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Inflammation and its Management

Additional Materials

Clarifications

  • Certain foods like processed meats, sugary beverages, and ultra-processed foods can increase inflammation due to their high levels of unhealthy fats, sugars, and additives. These foods can trigger the body's inflammatory response, leading to chronic inflammation if consumed regularly. It's important to limit the intake of these pro-inflammatory foods to help manage inflammation and reduce the risk of associated health issues. Incorporating anti-inflammatory foods like omega-3 rich foods, spices, and a plant-based diet can help counteract the effects of pro-inflammatory foods and promote overall health.
  • Chronic inflammation is likened to a car radio's volume that won't turn down, continuously escalating instead of subsiding. This analogy suggests that chronic inflammation persists and intensifies over time, much like a radio volume that keeps getting louder. The comparison highlights how chronic inflammation, if left unchecked, can lead to various health issues due to its prolonged and uncontrolled nature. By visualizing chronic inflammation in this way, it emphasizes the importance of managing and reducing inflammation to prevent long-term health complications.
  • Andrew Weil is a well-known American physician and advocate for integrative medicine, which combines conventional and alternative approaches to healthcare. He is the founder and director of the Arizona Center for Integrative Medicine at the University of Arizona. Weil is recognized for his work promoting holistic health practices, including the use of dietary supplements, herbal remedies, and mind-body techniques to support overall well-being.
  • Mushroom extracts are natural substances derived from various types of mushrooms that are believed to have medicinal properties. These extracts are often used in traditional medicine and are gaining popularity in modern wellness practices f ...

Counterarguments

  • While inflammation is a normal immune response, some researchers argue that in certain cases, it can be an overreaction of the immune system, leading to unnecessary damage to the body's own tissues.
  • The link between chronic inflammation and various health issues is complex, and some experts suggest that inflammation may be a symptom rather than a direct cause of some chronic diseases.
  • Lifestyle changes are important, but they may not be sufficient for everyone. Genetic factors, pre-existing conditions, and environmental exposures can also play significant roles in inflammation that lifestyle alone cannot address.
  • The impact of specific foods on inflammation can vary between individuals. Some people may not experience increased inflammation from processed meats, sugary beverages, or ultra-processed foods due to genetic differences or other factors.
  • The characterization of the mainstream North American diet as universally pro-inflammatory may overlook the diversity of dietary patterns within the population and the potential for healthy eating within this context.
  • While omega-3 rich foods and plant-based diets are often recommended for their anti-inflammatory properties, some studies suggest that the benefits may not be as significant as claimed, or ...

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No. 1 RISK FACTOR to Your Health: INFLAMMATION (What it is, & How to Reduce it)

The Importance of Sleep and its Effects

Adequate, high-quality sleep is crucial for physical and mental health

Sleep deprivation can negatively impact cognitive performance, decision-making, and mood regulation

Sleep is not simply a time to rest, but a critical period for health and daily functioning. Studies have shown that a lack of sleep can severely impair cognitive performance. For instance, sleep-deprived physicians made 20% more mistakes and took longer to complete their tasks by 14% in comparison to those who were well-rested. Moreover, sleep is essential for processing and connecting new information. It is during sleep that the neuronal connections associated with learning a new skill are solidified, suggesting that both cognitive performance and learning could be greatly hindered without adequate sleep.

Sleep plays a key role in immune function, metabolic regulation, and anti-aging processes

Li underscores the role of sleep in calming inflammation, which is linked to various aspects of health, including immune function and metabolic regulation. Fat cells, for instance, become more [restricted term] resistant without adequate rest, leading to an increased risk of belly fat and downstream metabolic issues. Sleep also acts as the most potent anabolic state filled with anti-aging hormones such as human [restricted term]. Additionally, sleep is imperative for the body's repair processes, with significant activities like the removal of metabolic waste occurring predominantly at night. Indeed, inefficient removal of metabolic waste is associated with a buildup of amyloid-beta plaque, a substance linked to Alzheimer's disease.

Developing consistent sleep habits, such as sticking to a schedule and minimizing light/screen exposure, can improve sleep quality

Expert Shawn Stevenson discusses how essential strategic sleep habits are, such as adhering to a schedule. Failing to do so can negate the intense efforts of training and diet, especially for athletes. It is while we are asleep that we experience heightened recovery from training and enhanced performance. Stevenson notes that when people are well-rested, they have better outcomes in terms of health and fitness. This is highlighted by a University of Chicago study where participants who were allowed more sleep lost 55% more body fat than those who were sleep-deprived, all under the same calor ...

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The Importance of Sleep and its Effects

Additional Materials

Clarifications

  • The glymphatic system is a waste clearance system in the brain that helps remove toxins and other waste products during sleep. It involves the flow of cerebrospinal fluid to clear out interstitial fluid and solutes from the brain and spinal cord. This system is crucial for maintaining brain health by flushing out metabolic waste and proteins that can contribute to neurological disorders. The glymphatic system's function is supported by astrocytic water channels and plays a role in brain waste removal and overall brain health.
  • Amyloid-beta plaque is an accumulation of a protein called amyloid beta outside brain cells. These plaques are associated with Alzheimer's disease and can lead to brain inflammation and neurological disorders. They form when amyloid beta proteins misfold and clump together, interfering with normal brain function. Amyloid plaques are a hallmark feature of Alzheimer's disease and are linked to cognitive decline and memory loss.
  • An anabolic state is a physiological condition where the body is focused on growth, repair, and recovery. During this state, processes like muscle building and tissue repair are prioritized. It is a crucial phase for functions like protein synthesis and the release of hormones that support growth and repair.
  • [restricted term] resistance is a condition where cells do not respond effectively to [restricted term], a hormone that helps regulate blood sugar levels. This can lead to elevated blood sugar levels and various health issues. Risk factors for [restricted term] resistance include obesity, a sedentary lifestyle, family history of diabetes, certain health conditions, and specific medications. Lifestyle changes like weight loss, exercise, and dietary adjustments can help improve or reverse [restricted term] resistance.
  • Metabolic waste consists of byproducts from the body's metabolic processes that are not needed and can be harmful if they accumulate. These waste products, like nitrogen compounds, need to be eliminated to maintain the body's chemical balance. Organs like the kidneys play a crucial role in filtering out and excreting these waste substances to keep the body healthy.
  • Cognitive performance encompasses mental abilities like thinking, learning, and memory. It relates to how well the brain processes information and makes decisions. Factors like attention, problem-solving, and language skills contribute to overall cognitive performance. Sleep plays a crucial role in maintaining and enhancing cognitive performance by supporting brain functions essential for optimal mental abilities.
  • Neuronal connections are the links between nerve cells in ...

Counterarguments

  • While adequate sleep is important, individual sleep needs can vary, and some people may function well with less than the often recommended 7-9 hours.
  • Cognitive performance can be influenced by factors other than sleep, such as stress, nutrition, and genetics, which can sometimes mitigate the effects of sleep deprivation.
  • The relationship between sleep and immune function is complex, and while sleep can support immune health, it is not the sole determinant of immune system effectiveness.
  • Metabolic regulation is influenced by a wide array of factors, including diet, exercise, and hormonal balance, not just sleep.
  • The role of sleep in anti-aging processes is not fully understood, and other factors like genetics and lifestyle choices may play a more significant role.
  • The effectiveness of consistent sleep habits can vary among individuals, and some may find rigid schedules counterproductive to achieving restful sleep.
  • The impact of sleep on athletic performance is multifaceted, and while important, it is only one of many factors that contribute to an athlete's success.
  • The gl ...

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No. 1 RISK FACTOR to Your Health: INFLAMMATION (What it is, & How to Reduce it)

Healthy and Unhealthy Foods and Beverages

Understanding the impact of our dietary choices is vital for maintaining good health. In the dialogue about what we consume, the distinction between beneficial and potentially harmful foods and beverages is increasingly important.

Sugary beverages like soda and fruit juices can significantly contribute to inflammation and other health issues

Sugary beverages are increasingly recognized as contributing to health issues, such as inflammation and damage to the gut microbiome. Andrew Weil's assertion about the importance of avoiding sweet liquids directly targets soda pop, fruit juices, energy drinks, and the sugar added to coffee and tea. Furthermore, William Li points out that diet sodas with artificial sweeteners may be even more harmful than those with sugar. He notes the detrimental effects of soda on our health, emphasizing that although natural sugars from fruits are generally okay because they come with other beneficial substances, high fructose corn syrup and similar sweeteners offer no such benefits.

The high sugar content and lack of nutrients in these beverages make them detrimental to overall well-being

The high sugar content in these beverages, often lacking in other nutrients, makes them particularly detrimental. Sugary drinks do not provide the antioxidants, fiber, or bioactives found in whole foods, which are essential for combating health issues and instead contribute to negative health outcomes.

Whole, minimally processed foods like vegetables, fruits, nuts, and whole grains should form the foundation of a healthy diet

Li advocates for the consumption of fruits and vegetables, highlighting their anti-inflammatory properties. Weil also references the way people in the past relied on real, scratch-made foods and not on manufactured or fast food. He suggests a major stride in improving health would be to curtail the intake of sweet liquids.

These nutrient-dense foods provide antioxidants, fiber, and other beneficial compounds that can counteract inflammation

The consumption of whole, minimally processed foods, which include a plethora of fruits and vegetables, as well as nuts and whole grains, is key to a healthy diet. These nutrient-dense foods are loaded with antioxidants, fiber, and various beneficial compounds that can actively counteract inflammation and support overall health.

Certain te ...

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Healthy and Unhealthy Foods and Beverages

Additional Materials

Clarifications

  • The gut microbiome consists of microorganisms like bacteria, fungi, and viruses that reside in the digestive system. It plays a crucial role in various bodily functions, such as digestion, immune system regulation, and even influencing mental health through the gut-brain axis. The composition of the gut microbiome can vary along different parts of the digestive tract, with the colon having the highest microbial density. These microorganisms help in metabolizing nutrients, protecting against pathogens, and maintaining overall gut health.
  • Bioactives are compounds found in foods that have a biological effect on the body beyond basic nutrition. They can promote health and help prevent disease by interacting with cells and enzymes. Examples include antioxidants, phytochemicals, and other functional components in plant-based foods. Consuming a variety of foods rich in bioactives is beneficial for overall health and well-being.
  • High fructose corn syrup (HFCS) is a sweetener made from corn starch. It is commonly used in processed foods and beverages as a cheaper alternative to sugar. HFCS contains varying levels of fructose and glucose, with different compositions like HFCS 42 and HFCS 55. The production and use of HFCS have increased due to factors like domestic sugar quotas and subsidies for corn production.
  • Antioxidants are compounds that help prevent oxidation, a process that can produce harmful molecules called free radicals. They are important for protecting cells from damage caused by oxidative stress. Common dietary antioxidants include vitamins A, C, and E, as well as other compounds found in fruits, vegetables, and teas. Antioxidants play a crucial role in maintaining overall health by neutralizing free radicals in the body.
  • Chlorophyll is a green pigmen ...

Counterarguments

  • While sugary beverages are linked to health issues, moderation is key, and occasional consumption may not significantly impact health for individuals with an otherwise balanced diet.
  • Some research suggests that diet sodas can be a better choice for weight management when compared to regular sodas, though the long-term effects are still debated.
  • The impact of sugar on health can vary greatly depending on the individual's metabolism, overall diet, and physical activity levels.
  • While whole, minimally processed foods are generally healthier, they can also be inaccessible or unaffordable for some populations, which can make a diet based on these foods challenging to adopt.
  • Some individuals may have allergies or intolerances to nutrient-dense foods like nuts or whole grains, requiring them to seek alternative sources ...

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