The authors elucidate that, despite common misconceptions, industrial hemp and marijuana both belong to the Cannabaceae family and fall within the Cannabis L. genus. * However, they differentiate "hemp" as the variety of cannabis grown predominantly for industrial uses such as the creation of fiber and seeds, whereas "marijuana" is the term used for the varieties cultivated for their psychoactive properties and significant levels of THC.
The authors point out that the key difference is the level of THC present. Industrial hemp is required to have a THC concentration that does not exceed 0.3%, which is insufficient to produce any psychoactive effects. Conversely, some marijuana varieties exhibit THC concentrations that can vary from 6% to 20%, and in certain instances, even surpass these figures. The considerable differences in the concentration of THC are what set their uses apart, with hemp being valued for its versatility in creating products like fabrics, paper, building supplies, and, in more recent times, for its therapeutic CBD attributes.
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The authors emphasize the discovery in the 1990s of a complex network of receptors and neurotransmitters that are essential for maintaining overall health and well-being, which is referred to as the endocannabinoid system. They describe the ECS as a crucial regulatory system, indispensable for sustaining and attaining balance within the body, which is key to optimal functioning, by influencing numerous important physiological processes.
The authors emphasize the essential function of the ECS in regulating diverse physiological processes including appetite, pain sensation, mood, memory, bone growth, and the body's immune responses. The human body inherently generates compounds like anandamide and 2-arachidonoylglycerol (2-AG), which, in conjunction with CB1 and CB2 receptors, primarily support the operation of this intricate control system. Endocannabinoids serve as signaling molecules that bind to specific receptors to maintain balance throughout various physiological...
The authors highlight the therapeutic advantages of cannabidiol (CBD), a non-psychoactive substance derived from hemp, and its importance in possibly mitigating numerous health conditions. They emphasize that CBD does not produce mind-altering effects, allowing individuals to benefit from its therapeutic properties without the high typically associated with marijuana use.
He explains how CBD interacts delicately with the body's intrinsic cannabinoid network, gently influencing its operations to promote balance and aid in healing. The authors emphasize a range of both preclinical and clinical studies that provide robust evidence of cannabidiol's efficacy in addressing a multitude of health concerns, underscoring its versatility as a therapeutic alternative.
The authors provide a comprehensive examination of the evidence backing CBD's therapeutic contributions, compiling an extensive summary of...
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The authors revisit the theory that a deficiency in endocannabinoids might play a role in the development of various chronic diseases, an idea first proposed by Dr. Ethan Russo and referred to as Clinical Endocannabinoid Deficiency Syndrome (CECD). They explain that when the body doesn’t produce enough endocannabinoids, or if there are problems with the functioning of cannabinoid receptors, the delicate balance within the ECS is disrupted.
The authors emphasize that this disequilibrium can result in a range of symptoms including ongoing pain, digestive issues, mood swings, anxiety, and sleep disturbances. They reference the research of Dr. Russo, emphasizing the importance of investigating the function of the body's cannabinoid receptor network in chronic conditions, as it is connected to a deficiency of natural cannabinoids in disorders like migraines, fibromyalgia, and irritable bowel syndrome.
The authors highlight the considerable evidence backing the therapeutic advantages of CBD, pointing out its efficacy in tackling numerous health concerns. they clarifie that preliminary studies conducted in laboratory settings and with animal subjects have laid the groundwork for understanding the potential healing benefits of cannabidiol. The authors emphasize research that demonstrates CBD's effectiveness in diminishing inflammation, along with its capabilities to cease seizures, mitigate stress, and safeguard neuronal cells.
Building on this foundation, the authors emphasize that human clinical trials have further confirmed the therapeutic benefits of cannabidiol, validating its use in treating conditions like epilepsy, anxiety, chronic pain, and multiple sclerosis. They emphasize the growing body of medical studies exploring the possibilities of CBD in managing complex diseases like Parkinson's, Alzheimer's, and various cancers.
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The authors explore the potential for marijuana dependency and acknowledges that while some individuals may develop a psychological or physical need for it, it typically poses a lower addiction risk compared to many commonly utilized substances. They cite statistics showing that approximately 11% of individuals who use cannabis might develop a dependency, a figure significantly lower than the addiction rates associated with nicotine, alcohol, and stronger substances like opioids and stimulants.
The authors emphasize the need for a balanced perspective while acknowledging the possibility of becoming dependent on marijuana. They underscore that the majority of cannabis users do not develop a dependency, and for the minority that might, the withdrawal symptoms are typically milder and less life-threatening compared to those linked to opioid or alcohol use.
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