Lysol, the household disinfectant, has a surprising backstory. In this episode of the Stuff You Should Know podcast, Chuck Bryant and Josh Clark explore Lysol's origins, its controversial history as an ineffective and potentially dangerous contraceptive, and its evolution into a household cleaner.
The hosts shed light on the current marketing of disinfectants like Lysol during the COVID-19 pandemic. They also delve into the potential health and environmental impacts of disinfectants, examining the "hygiene hypothesis" linking overly sterile environments to autoimmune diseases, and the exploration of alternative disinfection methods like UV light.
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Lysol was invented in 1889 by German chemist Gustav Raupinstrauch as a medical disinfectant containing 50% creosol in soap, as an alternative to the more toxic carbolic acid used at the time. Chuck Bryant and Josh Clark highlight that Lysol quickly gained popularity in hospitals and medical settings as an antiseptic.
However, by the early 1900s, concerns arose about Lysol's caustic nature causing patient burns and skin irritation. The AMA Council explicitly raised these concerns in 1912.
In a surprising marketing shift in the 1910s, Lysol's manufacturers repositioned the product for home "feminine hygiene" use as an illegal contraceptive. Bryant and Clark note it was promoted for use as a post-coital vaginal douche to prevent pregnancy.
Lysol became the most popular contraceptive in the U.S. from the 1930s to 1960s, despite being ineffective and potentially dangerous. A 1933 study cited by Clark found about 50% of 507 women using Lysol for contraception still became pregnant.
Exploiting women's insecurities through advertising, Lysol promotions suggested using it as key to marital satisfaction. However, its caustic cresol content led to inflammation, scarring, and even deaths from poisoning when used vaginally.
In the 1950s, Lysol transitioned away from contraceptive marketing towards safer use as a reformulated household disinfectant product.
Bryant and Clark describe how during the 2020-2021 COVID-19 pandemic, Lysol sales surged 12% as disinfectants were highly sought after, with 35 million cans produced per month in North America.
However, the CDC warned about potential long-term health impacts from excessive disinfectant use disrupting the microbiome. This highlighted the importance of safe, educated use despite record sales driven by the public health crisis.
The "hygiene hypothesis" posited by bacteriologist Graham Rook suggests the rise of autoimmune diseases may be linked to overly sterile modern environments killing microbes that help train the immune system. Supporting evidence comes from lower rates of such conditions in less industrialized areas.
Clark explains that Lysol contains quaternary ammonium compounds like benzalkonium chloride that destroy microbes by denaturing cells and coagulating proteins. At recommended potencies around 2.4%, they are effective germ-killers but highly concentrated forms pose ingestion and absorption dangers.
Emerging technologies like germicidal ultraviolet (GUV) light offer potential as disinfectants by using a far-UV spectrum that cannot penetrate human skin and eyes. However, they may create indoor air pollution via ozone production when interacting with other particles.
1-Page Summary
Lysol, a product known worldwide for its disinfecting properties, has its roots in the late 19th century. It originated from the pursuit of combating infectious diseases in medical settings.
Invented in 1889 by German chemist Gustav Raupinstrauch, Lysol was intended to act as a medical disinfectant to help control infectious diseases and save lives.
Lysol's initial formula comprised 50% creosol in soap, forming a brown-colored germ-killing solution. This was a significant development as creosol was considered less poisonous than the formerly used carbolic acid, making Lysol a safer option for disinfecting purposes at the time.
Lysol became widely recognized and used as an antiseptic in medical facilities. However, despite its popularity, concerns about its safety began to surfac ...
Lysol's Origins and Early History
In an astonishing twist of historical marketing, Lysol, now a household disinfectant brand, was once controversially repositioned as a women's contraceptive. This repositioning led to widespread use and serious health consequences.
In 1912, as hospitals ceased the use of Lysol due to safety concerns, the manufacturers decided to target women for home use, specifically for cleaning reproductive organs. This shift in marketing portrayed Lysol as a preventative solution for pregnancy.
The ability to market Lysol as a "feminine hygiene" product covertly allowed it to be pitched as an illegal contraceptive method. Chuck Bryant and Josh Clark highlight that Lysol was ultimately marketed to women as a post-coital vaginal douche to prevent pregnancy. The term "feminine hygiene" itself became a euphemism for contraception through douching.
Clark underscores the ineffectiveness of this method with a study from 1933, which pointed out that of 507 women using Lysol for contraception, about half became pregnant. However, it remained in use as a contraceptive until the 1960s, when the introduction of the pill brought about its abrupt discontinuation for this purpose.
Lysol’s marketing campaigns played on gendered insecurities to sell the product, suggesting that a woman's desirability and marital satisfaction hinged on her "cleanliness." Ads portrayed scenarios where lack of use led to a loss of m ...
Lysol's Controversial Use as a Contraceptive
Lysol has evolved from its controversial history as a marketed contraceptive to being part of everyday household cleaning, especially noted during the 2020-2021 COVID-19 pandemic.
In the 1950s, Lysol began to pivot away from marketing its product as a contraceptive, a use that had dangerously misled many consumers. The brand reformulated its product to be less toxic, replacing harmful ingredients like creosol with safer chemicals, to promote its use more responsibly as a household disinfectant.
During the onset of the COVID-19 pandemic, Lysol sales soared, with a notable 12% increase in just one year and the company producing 35 million cans per month in North America. Specifically recommended by the CDC for its effectiveness against COVID due to its ingredient benzalkonium saccharate, Lysol became a staple in pandemic mitigation measures.
However, as the pandemic eased and daily life began to return to some sense of normalcy, people started to stow away their cans of Lysol, leading to a subsequent decline in sales. Despite the increase in sales and widespread adoption of the product, Lysol and other disinfectant brands took the step of warning against the ingestion of their products, reacting to some errant advice ...
Lysol's Evolution as a Household Disinfectant Brand
An examination of the increased use of disinfectants like Lysol reveals both potential health repercussions for individuals and wider environmental impacts. The "hygiene hypothesis" suggests that this surge could be contributing to a rise in autoimmune diseases due to reduced exposure to necessary microbes.
The hygiene hypothesis posits that overly sterile conditions in industrialized countries might predispose individuals to autoimmune diseases due to a lack of exposure to a variety of germs during childhood. Bacteriologist Graham Rook suggested that the human immune system has evolved with certain microbes, essential for immune system training, which are wiped out by disinfectants. Studies, such as one comparing Finnish, Estonian, and Russian children, found that those from the more industrialized countries had immune systems less exposed to microbes like E. coli, which are necessary to promote a healthy immune response. Clark also remarks that autoimmune diseases became more prevalent after the generation that began using disinfectants, pointing to a significant circumstantial evidence.
High disinfectant use in the U.S. could be problematic if it is indeed killing beneficial microbes that help train our immune system. Comparative studies show lower rates of conditions like food allergies and type 1 diabetes in less developed countries, where there is less exposure to disinfectants and a greater variety of microbial exposures.
Disinfectants work by destroying microbes' protective layers, causing them to die. Lysol contains a quaternary ammonium compound (QAC) called benzalkonium chloride, potent at concentrations as low as 2.4%. When combined with alcohol, QACs become even more effective at killing germs. These substances can denature cells and coagulate proteins, wiping out bacteria.
For disinfectants to be effective, they need to be used at a minimum inhibitory concentration. Lysol is often used at a potency of 2.4%, with recommended conta ...
The Potential Health and Environmental Impacts of Disinfectant Use
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