#175 Dr. Gabrielle Lyon - The Nicotine Debate, Aging Conspiracies and Living to 100

Gabrielle Lyon and Shawn Ryan address the crucial role of early detection in cancer treatment and discuss advanced technologies that have improved these efforts.

MRI, Liquid Biopsy Detect Cancer In Early, Treatable Stages

Gabrielle Lyon highlights the emergence of new screening techniques that are enhancing early cancer detection. She specifically mentions full-body MRI scans and liquid biopsy tests, such as the Prunovo scan and the gallery test (originally called the grail). These innovations allow healthcare professionals to identify cancer at its earliest and most treatable stages.

Early Detection Improves Outcomes; Many Cancers Are Treatable if Caught Early

Both Lyon and Ryan advocate for the regular use of these screening tools based on evidence that early detection significantly improves outcomes. They point out that for a variety of cancers, such as colon cancer, the recommended age to begin regular screenings like colonoscopies has been lowered from 50 to 45 years old. The primary benefit is that precancerous conditions can be identified and treated before developing into full-blown cancer.

Military at Higher Cancer Risk From Environmental Exposure

Lyon reveals that individuals in the military may experience higher rates of cancer due to environmental exposures. She mentions a paper they published on b ...

Gabrielle Lyon discusses the importance and nuances of hormone optimization and replacement therapy, with a focus on ensuring accessibility, battling stigma, and taking an individualized approach to treatment.

[restricted term] Therapy Boosts Men's Health and Vitality With Age

[restricted term], important for preserving muscle, sexual function, and overall wellness, becomes crucial as men age. Dr. Lyon touches on the challenges in providing hormone replacement therapy, even for active military personnel.

Optimal [restricted term] Levels Preserve Muscle, Sexual Function, and Wellness

Lyon states that high levels of free [restricted term] are beneficial. While lab ranges dictate what is considered "normal," the goal is to strive for a higher free [restricted term] number. Lyon addresses society's perception of [restricted term] replacement therapy, which is stigmatized partially due to drug scandals in sports. Contrary to some beliefs, [restricted term] replacement therapy does not cause prostate cancer, as research by experts like Abe Morgentaler and Dr. Mohit Khera has found, and the Traverse Trial indicates it does not increase the risk of negative cardiovascular outcomes.

Shawn Ryan and Gabrielle Lyon discuss the potential for men to maintain [restricted term] levels similar to those at age 25 into old age. Lyon believes it is possible, citing the example of her father who, at age 74, maintains a [restricted term] level of 750, attributing it to a lifestyle that includes frequent walking and living in nature.

Hormone Replacement, Including Women's [restricted term], Prevents Age-related Sexual and Tissue Health Decline

Hormone therapy includes treating women with [restricted term] for improved sex drive, balanced hormone levels, and maintained muscle mass. [restricted term], when prescribed correctly, can also have benefits. Measuring IGF-1 levels is a crucial aspect of hormone optimization, including [restricted term] therapy. Dr. Lyon emphasizes hormone replacement for women to maintain sex drive and protect vaginal tissue from atrophy.

Providers Should Take an Individualized Approach to Hormone Optimization Over Generic Guidelines

Gabrielle Lyon underscores the importance of a tailored approach to hormone therapy contrary to generic guidelines. She notes the importance of considering individual needs and the effect of hormone receptors' sensitivity, which varies from person to pers ...

Shawn Ryan and Gabrielle Lyon discuss critical aspects of diet and supplementation and their impact on health and longevity. They underscore the importance of awareness of what we consume, how our diet relates to health issues like obesity and cancer, and the role of supplements in supporting nutrition and bodily function.

Balanced Plant-Animal Whole Foods Diet Ideal For Longevity

Gabrielle Lyon suggests that a dietary balance of both plant and animal-based foods is crucial for longevity. She suggests that muscle maintenance requires sufficient animal protein intake, recommending foods like red meat, salmon, and organ meats. In discussing historical context, she notes the recognition of dietary protein's importance during World War II, with soldiers rationed significant amounts of meat per week, something she sees as starkly contrasting with today's guidelines.

Processed Foods, Seed Oils, and Sugar Harm Health

Lyon criticizes current dietary trends that lean toward a predominantly plant-based diet due to processed foods, which she believes we are not aging well because of. She also delves into controversies around seed oils, suggesting concerns about inflammation and unnatural consumption, especially when these oils are used in pastries, baked goods, and fried foods. Moreover, she characterizes the average American diet, heavy in pizza and potato chips, as a "suicide diet," leading to a host of health problems.

Supplementation Supports Nutrition and Bodily Function

Dr. Lyon acknowledges the diminished nutritional value of modern produce and advocates for supplementation to fill the gap. She discusses the benefits of gut health for nutrient absorption and recommends colostrum for its gut-healing properties and its contribution to the immune system.

High-Quality Supplements: Greens Powders, Colostrum, Creatine Benefits Beyond Multivitamins

Lyon occasionally uses greens powder due to her low vegetable intake and advocates for the use of high-quality supplements that serve specific purposes, like AG1 which she likens to a multivitamin. Furthermore, she discusses creatine's benefits for cognition and memory, indicating its potential importance in brain health as we age.

Colostrum is described by Lyon as a nutrient-rich mother's milk with excellent data supporting its use for enhancing gut health. She relates her positive personal experience with colostrum to gut sensitivity issues she faced. Lyon also notes that she supplements her diet with ...

Gabrielle Lyon and Shawn Ryan discuss the critical importance of sleep and circadian rhythms for maintaining health, preventing disease, and contributing to longevity.

Optimized Sleep Enhances Performance and Prevents Disease

Gabrielle Lyon highlights that good sleep hygiene is crucial for brain function, overall performance, and disease prevention, including metabolic issues and dementia.

Key To Regulating Circadian Rhythms: Consistent Sleep and Avoiding Night Light Exposure

Lyon asserts that sleep is essential for the brain to process information and cleanse itself. Lyon stresses the importance of getting seven to eight hours of sleep for most people, noting that a handful with a genetic mutation can function well on about four hours. She shares a personal anecdote about how lack of sleep once led to an increase in her blood sugar levels, further connecting adequate sleep with disease prevention.

Gabrielle Lyon believes that the field of sleep biology is expanding into circadian biology, which examines sleep patterns in alignment with natural rhythms. Aligning eating patterns and light exposure wit ...

Gabrielle Lyon and Shawn Ryan discuss the psychological and behavioral traits of high-performers, emphasizing the importance of mental toughness, continuous learning, emotional neutrality, and personal standards.

Stable High Performers Avoid Emotional Extremes

Cultivating a Neutral Mindset Through Restriction and Moderated Celebration

Gabrielle Lyon has observed a pattern of neutrality among highly successful individuals. She describes these individuals as maintaining an even keel, staying neutral regardless of whether things are going great or terribly. She explains that those who can maintain a neutral mindset tend to be the most successful. Lyon observes that people who get extremely excited about events can peak emotionally, which leaves them vulnerable to falling just as low when things turn sour. She shares an example of a patient who would become depressed after hosting a big event, despite making millions. Lyon suggests avoiding emotional highs to prevent subsequent lows, delineating purposeful restriction as a means of maintaining emotional neutrality.

Successful People Set Standards and Avoid Distractions

Lyon stresses that managing distractions is critical, citing that distraction can be even more detrimental to success than personal health issues. She recounts a personal incident at a pool where a momentary distraction could have resulted in her son drowning, to illustrate the consequences of not keeping focused.

Shawn Ryan affirms the importance of doing one thing well, instead of being distracted by multiple things, leading to greater success in his podcasting ventures. Both Lyon and Ryan emphasize the significance of discernment, including discerning the right actions to take and thoughts to focus on according to personal standards.

Core Values and Purpose Guide High-Performers' Choices

Lyon states that successful people establish standards, not merely goals, because standards connote a consistency of action that is not influenced by individual outcomes. Daily actions, such as training regularly and execute key ...