The Cover Up podcast dives into the chilling anthrax attacks of 2001 and the investigation's surprising connections to a United States Army biodefense lab. The episode examines the history of bioweapons research that preceded the transition to defensive study at USAMRIID. It details the complex collaboration between the lab's scientists and the FBI, leading to a breakthrough that genetically linked the anthrax used in the attacks to a specific flask from USAMRIID.
As suspicion grows around one of the lab's top anthrax experts, Bruce Ivins, the episode delves into the tensions between investigators pursuing different leads. It highlights the challenges faced in tracing such a lethal and rare pathogen to its source, raising questions about the investigation's focus on a single suspect.
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Following the 1969 Bioweapons Treaty signed by President Nixon, the U.S. transitioned from developing bioweapons to defensive research at USAMRIID. Despite housing dangerous pathogens, Jeff Adamovicz and Hank Heine noted USAMRIID had a surprisingly casual culture with lax security measures.
During the 2001 Amerithrax anthrax attacks investigation, the FBI enlisted USAMRIID microbiologists like Bruce Ivins, a top anthrax expert, for their expertise. These scientists were dedicated to assisting the FBI, though tracing anthrax sources via genetic analysis proved challenging.
An accidental discovery at USAMRIID revealed distinctive "morphs" - rare anthrax mutations that can visually link samples to their source lab. FBI sampling found only 8 samples matching the attack letters' morphs, all traced to a flask (RMR-1029) at USAMRIID.
Bruce Ivins drew suspicion for unauthorized anthrax cleanup, his presence at key evidence sites, and being RMR-1029's custodian. Submitting an incorrect sample to the FBI further heightened suspicion of his involvement.
Rick Lambert, the Amerithrax lead investigator, was unconvinced of Ivins' guilt and wanted to investigate other potential sources like Dugway and Battelle. However, FBI pressure mounted to focus solely on Ivins despite Lambert's reservations.
1-Page Summary
USAMRIID's evolution from bioweapons research to a defensive focus is a critical element of its history, along with concerns about the laxity of its security measures.
In 1969, the United States, following the International Bioweapons Treaty signed by President Richard Nixon, pledged to cease developing bioweapons. This commitment led to the restructuring of the Fort Detrick bioweapons program into the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). The facility transitioned its focus solely to defense-oriented research, aiming to protect against potential biological threats rather than create them.
With the signing of the treaty, USAMRIID began directing its expertise and resources toward defensive measures against infectious diseases and potential bioterrorism, reflecting a global shift in stance on the production and use of biological weapons.
Despite its critical role in biosecurity, USAMRIID had surprisingly relaxed measures in places, placing trust in the professionalism of its staff and the unspoken rule of responsibility given the nature of the work conducted there.
Jeff Adamovicz and Hank Heine observed that, during their tenure, the culture among USAMRI ...
History of bioweapons research and USAMRIID
During the Amerithrax investigation, the complex and high-stakes nature of the case necessitated a unique collaboration between the FBI and USAMRIID scientists, who provided crucial expertise.
In 2002, the FBI's Amerithrax squad, led by John Kerr, recognized that the expertise needed for the investigation exceeded what the FBI laboratory could provide. The murder weapon was a rare and dangerous bacteria, anthrax, which required specialized knowledge and facilities to study. The FBI turned to a group of renowned microbiologists with federal security clearance to assist in the case.
These scientists, from the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), had been helping with the Amerithrax investigation almost from the outset. Among them was Bruce Ivins, one of the leading anthrax experts in the world. Ivins was tasked with evaluating the anthrax spores found in a letter addressed to then-Senator Tom Daschle the day after it arrived at USAMRIID.
Ivins and his colleagues from the microbiology department at USAMRIID demonstrated deep commitment to assisting the FBI with understanding the scientific aspects of the anthrax attacks. Hank Heine, a fellow microbiologist, recounted that for approximately two and a half years, the department felt integral to the team's efforts to resolve the case.
Collaboration between USAMRIID and the FBI in the Amerithrax investigation
An accidental discovery in a USAMRIID lab has enabled a significant forensic breakthrough by using anthrax "morphs" to potentially trace the source of anthrax samples.
When a USAMRIID technician named Terry inadvertently left anthrax samples in the incubator for a longer time than usual, the spores developed distinctive appearances. Rather than the typical small, puffy white clouds, these spores spread out, had defined edges, and took on a yellowish tint. This overgrowth led to the identification of "morphs," defined as morphological variants. These are rare mutations that occur when bacteria reproduce, often resulting in highly informative distinguishing characteristics between different types of anthrax.
The significance of these morphs lies in their unique and identifiable features, which offer a new method to distinguish anthrax samples from each other. USAMRIID scientists were previously stymied by the fact that anthrax usually replicates in the same way each time, rendering DNA analyses of samples from different labs almost identical. The discovery of morphs, therefore, provided a vital forensic tool, akin to "a hair or a fiber or a fingerprint," which could link a specific strain of anthrax back to its source laboratory.
The forensic breakthrough with anthrax "morphs"
Bruce Ivins, once known for his quirky and eccentric behavior, became a person of interest in an intense FBI investigation due to his questionable actions surrounding anthrax samples.
Bruce Ivins was no stranger to unusual behavior, often engaging in light-hearted pranks and expressing his passions in creative ways, whether through juggling or charming colleagues with music and song. His intensity about hobbies and interests sometimes required colleagues to bluntly tell him to quiet down, and on one occasion, his superior had to autoclave his fungally-infected tennis shoes due to contamination concerns.
However, his quirky persona took a darker turn when he conducted unauthorized actions in the lab. Ivins carried out clean-up operations outside the scope of what was allowed, swabbing areas outside of the containment zones after a leak of anthrax. This action, particularly cleaning up stray spores in his own office without authorization, caught the attention of the FBI. Additionally, his unexpected presence at a pond dredging operation key to the Amerithrax investigation further raised suspicions about his involvement.
As a preeminent scientist in pathogenic microbiology and developer of an anthrax vaccine, Ivins held a significant position within his field. This status came with the responsibility of being the sole custodian of the RMR-1029 flask, containing the very anthrax spores used in the attacks. His activities and history at the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) came under intense scrutiny.
The FBI harbored suspicions about Ivins over what seemed to be an attempt to clean his office and potentially destroy evidence. Ivins ...
Suspicion and investigation of Bruce Ivins
Rick Lambert, lead investigator of the Amerithrax case, was unconvinced that Bruce Ivins was the culprit behind the anthrax attacks and faced pressures from FBI leadership to focus exclusively on him.
During a March 2005 interview with Ivins, Rick Lambert noted his mild-mannered and cooperative nature, and when confronted about the anthrax mutations linked to his lab, Ivins responded in a way Lambert felt an innocent person would. Lambert's suspicions about Ivins were neither heightened nor dispelled following the interview, leaving him unconvinced of Ivins' guilt due to the lack of a definitive "smoking gun." Lambert informed FBI Director Mueller of his position, stating that the circumstantial evidence against Ivins did not amount to probable cause for charges.
Lambert pressed to extend the investigation beyond USAMRIID, but faced resistance. He harbored concerns about the possibility of broader access to the anthrax strain and the casual sharing of anthrax spores among researchers, indicating that other facilities, such as Dugway Proving Ground and the Battelle Institute, were equally compelling sources. Both Dugway and Battelle had access to anthrax with the same morphological variants as those found in the attack letters.
Lambert was especially critical of the incompleteness of anthrax submissions from these facilities and believed direct sampling by FBI agents with search warrants would have been more appropriate. Desp ...
Tensions within the Amerithrax investigative team
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