A woman full of energy, standing on a beach and holding her arms out wide, illustrates how to improve your metabolic health

Is your metabolism holding you back? Would you like to boost your energy and improve your overall health?

Lifestyle changes alone can enhance your metabolic health. Psychiatrist Christopher M. Palmer shares practical strategies—from exercise and sleep to diet and stress management—that can make a significant difference in your physical and mental health.

Keep reading to unlock the secrets of how to improve your metabolic health and transform your life.

Treatments to Improve Your Metabolic Health

Palmer asserts that, to improve your metabolic health, you must replace unhealthy lifestyle habits that harm your mitochondria with healthier ones. By addressing issues related to metabolism through lifestyle changes, you can reduce risk factors and treat mental disorders more effectively. He provides concrete advice on how to improve your metabolic health with these changes, and then he shares tips on easing them into your life one at a time.

#1: Exercise Regularly

Palmer writes that based on studies, one way to improve your metabolic health is to exercise regularly. To get the most metabolic benefit from exercise, aim to challenge yourself physically rather than just doing leisurely activities. Palmer argues that pushing your body helps improve the health of your mitochondria, so instead of a slow-paced bike ride, consider alternating between bursts of intense cycling and rest, for instance.

(Shortform note: In Outlive, Attia offers a similar perspective on exercise and metabolic health. He recommends “Zone 2” aerobic exercise, which is light to moderate in intensity. This type of exercise, according to Attia, helps produce more high-quality mitochondria in your cells, improving their ability to burn fat and glucose. Attia suggests at least three hours of Zone 2 exercise per week for the average person.)

However, Palmer notes that if you already have health conditions or metabolic dysfunction, you might not experience the full positive effects of exercise. For example, insulin resistance can limit or even negate the benefits of exercise. However, Palmer still suggests exercise as a way to either improve or at least maintain your metabolic health.

(Shortform note: The inability to exercise (and reap the benefits of exercise) due to health issues like metabolic dysfunction is known as exercise intolerance. It occurs when problems with the heart, lungs, or muscles reduce the body’s ability to take in oxygen, distribute it via the bloodstream, or use it efficiently in the muscles during physical activity. Exercise intolerance is common, affecting around half of the over six million Americans with heart failure for example. The best treatment is usually a personalized exercise training program, with the intensity tailored to your condition.)

#2: Get Good Sleep

In addition to improving your diet and exercise, Palmer writes that getting enough quality sleep is crucial for maintaining a healthy metabolism. During sleep, your body undergoes various processes to rest and heal itself. Thus, when you deprive yourself of quality sleep, you disrupt these processes and, consequently, the maintenance and growth of your mitochondria.

(Shortform note: In Sleep Smarter, Shawn Stevenson explains that your brain’s waste removal system, called the glymphatic system, is 10 times more active when you’re asleep than when you’re awake. During sleep, your brain cells shrink by about 60%, making this cleaning process more efficient. If you don’t get enough quality sleep, your brain can’t properly remove these waste products, toxins, and dead cells. Over time, this buildup can lead to major health problems, including Alzheimer’s disease.)

Palmer writes that you can improve your sleep by fixing your circadian rhythm. Your circadian rhythm is your body’s internal sleep-wake clock—it determines when you feel awake and when you feel sleepy. To fix your circadian rhythm and get better sleep, get natural light during the day and limit light exposure at night. Every morning, regulate your circadian rhythm by exposing yourself to direct sunlight for about 30 minutes. At night, help your body prepare for sleep by staying away from lights, such as technology screens.

(Shortform note: The discovery of the circadian rhythm dates back to the 18th century. A French scientist noticed that mimosa plants opened and closed their leaves at regular times, even when kept in constant darkness. This suggested that plants had an internal clock. Later research identified the specific genes controlling the circadian clock. So while light is the main cue, circadian rhythms are an intrinsic part of your biology.)

#3: Develop a Sense of Purpose

Palmer suggests you manage stress better by cultivating a sense of purpose to improve your mental and metabolic health. This sense of purpose can come from various sources, such as spiritual beliefs, personal goals, or community involvement.

Chronic stress takes a toll on your brain’s ability to function properly, affecting cognitive processes like focus, learning, and memory. This is because stress consumes a significant amount of your brain’s energy resources, meaning it has less energy available for other critical tasks like cellular maintenance. Over time, this lack of proper maintenance can lead to more serious issues with your brain’s health and functionality.

Palmer explains that people who have a clear understanding of their life’s meaning tend to manage stress more effectively. Also, when you have a strong sense of purpose, you’re more likely to make healthier lifestyle choices. Thus, make it a priority to reflect on what gives your life meaning, and pursue activities aligned with that purpose. For instance, if you find meaning in creative expression, regularly engaging in art or music could help reduce stress and improve your mental state.

Other Ways to Combat Chronic Stress

In Mind Over Medicine, Lissa Rankin elaborates on Palmer’s discussion of chronic stress, explaining that stress causes your body to go into “fight-or-flight’ mode. While this response can help you survive life-threatening situations, chronic stress keeps your body in a constant state of emergency. Over time, this doesn’t just affect your brain, but it also damages your blood vessels, causes plaque build-up, increases heart attack risk, weakens your immune system, and leads to muscle stiffness and structural problems.

Rankin says that positive beliefs and relaxation activate your “rest and repair” response, allowing your body to focus on important maintenance tasks like digestion, cell repair, and boosting your immune system to fight disease. In addition to developing a sense of purpose, as Palmer suggests, consider some of Rankin’s suggestions for managing stress.

1. Accept negative emotions. Rankin explains that it’s normal and inevitable to experience feelings like sadness, anger, and fear at times. By acknowledging these feelings rather than suppressing them, you can process them more effectively and let them pass. This helps prevent these emotions from spiraling into chronic stress.

2. Meditate. Regular meditation can lower blood pressure, boost immunity, and activate areas of your brain associated with creativity, happiness, and empathy. At the same time, it calms the amygdala, the part of the brain that triggers the stress response.

3. Develop your spirituality. Rankin suggests you acknowledge the sacred in everyday life, trust in a higher power to guide your healing journey, and follow a spiritual path true to your values. She notes that being a part of a spiritual community is linked to better mental health and longevity. Reflecting on what gives your life meaning, as Palmer advises, can be a good starting point for developing your spirituality.

#4: Evaluate Your Medications 

Palmer recommends you learn about how your medications affect your metabolism, especially how they affect your hormones and neurotransmitters. Commonly prescribed medications like some antidepressants, anti-anxiety medications, antipsychotics, and hormonal treatments can have varying effects on mitochondrial function. For example, some antidepressants might boost serotonin levels, which could potentially improve mitochondrial function in some people. Conversely, some antipsychotic drugs designed to calm hyperexcitable symptoms can also suppress mitochondrial function as a side effect.

(Shortform note: In the short term, antidepressants can reduce appetite and cause weight loss by increasing serotonin levels as Palmer suggests. However, long-term use can cause a decrease in the number of your body’s serotonin receptors, which increases cravings for carbohydrate-rich foods and can lead to weight gain. Moreover, in addition to causing weight gain, antipsychotics can also lead to other health issues like high blood sugar, high cholesterol, and high blood pressure.)

While Palmer encourages you to be proactive in understanding your medications, he advises against making any changes without professional guidance. Abruptly stopping or changing medications can have serious consequences for your health. So, if you have concerns about how your medications might be affecting your metabolism or energy levels, discuss these issues with your doctor to explore potential alternatives or adjustments.

(Shortform note: The emerging field of pharmacogenomics studies how your DNA affects your response to medications. Your genes can influence how your body processes medications in several ways. For instance, your DNA determines the types and numbers of receptors in your cells, which can affect how well a drug works for you. It also impacts how quickly your body breaks down drugs, which can influence the dosage you need. In some cases, your genetic makeup might mean a particular drug won’t work for you at all. Understanding your genetic profile could help your doctor choose medications that are more likely to work well for you and less likely to cause harmful metabolic side effects.)

#5: Improve Your Diet

Palmer writes that eating a nutritious diet can improve your metabolic and mental health. He explains that dietary quality has declined over the last 50 years: On the whole, we’re eating more low-fiber, high-sugar junk food. A lack of nutritious foods in your diet can lead to mental and neurological disorders because your mitochondria need enough nutrients to function well. Additionally, many of these foods can lead to addictive eating habits, which in turn may result in obesity and insulin resistance, further affecting your metabolism.

To improve your diet, Palmer suggests you do four things.

1. Correct nutritional deficiencies. Eat a diet rich in whole foods and high-fiber foods like fruits and vegetables. Consider consulting a professional to identify deficiencies in essential vitamins, minerals, and other nutrients in your diet.

2. Avoid inflammatory substances. Palmer says certain foods like junk food and trans fatty acids (TFAs) contain toxic substances that cause inflammation, which impedes your metabolic functioning. Some people may also need to avoid common allergens like gluten or dairy that can trigger immune reactions. Additionally, heavy use of drugs and alcohol can also harm your metabolic health.

3. Improve gut health. Palmer writes that probiotics may help boost your gut health, but research isn’t conclusive. Avoid antibiotics and foods that contain antibiotics, as these disrupt your gut microbiome.

4. Consider diets and fasting. Palmer cites research suggesting that the Mediterranean diet, which focuses on whole grains, vegetables, fruits, and healthy fats, improves mitochondrial functioning. The ketogenic diet (a high-fat, low-carb eating plan) and intermittent fasting (which involves cycling between periods of eating and fasting) can also improve metabolism and brain functioning.

How to Get Started on Treating Your Metabolism

To start treating your metabolic issues, Palmer suggests you try one metabolic treatment at a time for at least three months so your body has time to adapt. For example, you could start by adjusting your diet, focusing on whole foods and reducing processed items. 

If after three months you notice even slight improvements, Palmer recommends sticking with that intervention. But, if you don’t see any benefits, it’s OK to move on and experiment with a different approach, such as improving your sleep routine. If you’re seeing partial improvement to your metabolic health with one treatment, consider adding another to the mix, as this could help address symptoms more comprehensively.

Palmer notes that when you first begin treating underlying metabolic problems, it can disrupt your body’s metabolic balance. While this transition may feel uncomfortable initially, it’s a necessary part of the healing process. Your body needs time to adapt and establish a new baseline. As you continue with the interventions, Palmer suggests slowly increasing the intensity or dosage to support your body’s ongoing adaptation. This gradual increase allows your body to continuously adapt without being overwhelmed, enhancing the effectiveness of the treatment over time.

(Shortform note: As you embark on your metabolic treatment process, consider ways to monitor your progress, such as by keeping a symptoms journal to monitor your metabolic health over the three-month periods—track any changes in how you feel day-to-day, and record details like your diet, sleep, exercise, mood, and any symptoms you experience. Another way is to use wearable technologies, an emerging way to track health biomarkers like blood sugar or cortisol levels. Studies show that 46% of people who track health indicators say it has changed their overall approach to maintaining their health. Many report that health tracking has led them to ask their doctor new questions, seek second opinions, and make different treatment decisions.)

For those dealing with serious mental health conditions, Palmer recommends considering inpatient or residential treatment programs that provide more intensive, round-the-clock support. These settings can offer intensive, structured support for those who need more comprehensive care than outpatient treatments can provide. Work with a mental health professional to determine if a higher level of care is appropriate.

(Shortform note: There are resources that can help you find inpatient or residential treatment facilities. The Substance Abuse and Mental Health Services Administration (SAMHSA) offers a Treatment Locator that can help you find facilities based on factors like insurance, cost, and type of treatment. Other resources include the American Residential Treatment Association’s facility locator and FindTreatment.gov, which let you search for treatment centers by location and filter results based on your specific needs.)

Exercise: Evaluate Your Metabolic Health 

Palmer’s brain energy theory suggests that your mental health is closely linked to your metabolic health. Examine your current lifestyle habits and identify areas that might be impacting your metabolic functioning to improve your overall health and well-being.

  1. How would you describe your current diet? Reflect on the types of foods you regularly consume and whether they align with Palmer’s recommendations for a nutritious, whole-food based diet.
  2. What’s your current exercise routine like? Consider both the frequency and intensity of your physical activities, and how they might be affecting your mitochondrial health.
  3. How would you describe your sleep patterns? Think about your bedtime routine, the quality of your sleep, and whether you’re exposing yourself to natural light during the day and limiting artificial light at night.
  4. How do you currently manage stress in your life? Reflect on whether you have a sense of purpose or engage in activities that give your life meaning.
  5. Based on your reflections, what is one specific area that you think could have the most significant impact on your metabolic health if improved? How might you go about making this change?
How to Improve Your Metabolic Health: 5 Lifestyle Changes

Elizabeth Whitworth

Elizabeth has a lifelong love of books. She devours nonfiction, especially in the areas of history, theology, and philosophy. A switch to audiobooks has kindled her enjoyment of well-narrated fiction, particularly Victorian and early 20th-century works. She appreciates idea-driven books—and a classic murder mystery now and then. Elizabeth has a blog and is writing a book about the beginning and the end of suffering.

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